In Bcr-Abl+ leukemia, hypoxia-adapted (HA)-Bcr-Abl+ cells exhibiting stem cell-like characteristics showed higher GLO1 expression and enzymatic activity, and GLO1 inhibitors effectively suppressed the viability and capacity for tumor formation of this HA-Bcr-Abl+ cells [34]. The gene discussed is GLO1; the disease is neoplasm.