The percentage of CD206+iNOS- M2 macrophages was lower in the cSCC of OSM-KO mice than those of WT mice (Figure 7A), as well as the total number of M2 macrophages in the tumor, which was also significantly lower (65%) for OSM-KO than WT mice (Figure 7B), whereas there was no difference in the M1 macrophage count. The gene discussed is OSM; the disease is neoplasm.