ADM and Sepsis: It is stated that the neopterin and pro-ADM is useful for detecting infection and severity of illness.21,22 The upper limit of serum neopterin level was shown as 10 nmol/L in healty individuals and it was reported that neopterin could be a useful marker in predicting infection and gram negative sepsis.23 In patients with sepsis, mean neopterin level was found 75.7 nmol/L and shown to be significant predictor of bacteremia.21 The pro-ADM cutoff value was calculated as 1 nmol/L to distinguish septic patients from healthy individuals.