With an estimated population of 701,000 Greek Cypriots (Cyprus statistical service 2016_ http://www.mof.gov.cy/mof/cystat/statistics.nsf/populationcondition_21main_puparchive_en/populationcondition_21main_puparchive_en?OpenForm&yr=2016) and the recent report by our group that the true carrier frequency of CYP21A2 in Greek-Cypriots is 1:10 (18), the CAH prevalence is therefore predicted to be around ~1750 (701,000 × 1⁄2 × 1⁄2 × 1/10 × 1/10 = 1752.5). Here, CYP21A2 is linked to congenital adrenal hyperplasia.