Other transcription factors had wide-scale roles in different processes, e.g., FoxJ2 is an important regulator of dopaminergic neurons (Wijchers et al., 2006) and Oct1 (Pou2f1) polymorphisms associated with Alzheimer’s disease (Taguchi et al., 2005). This evidence concerns the gene FOXJ2 and early-onset autosomal dominant Alzheimer disease.