To verify this hypothesis, we first tested the expression of SCD1 in stable melanoma cells lines with different sensitivity to vemurafenib (A375 (IC50 value 0.002 μM), M14 (IC50 value 0.13 μM), M14-R (IC50 value 0.25 μM) and WM115 (IC50 value 2.59 μM)), previously evaluated by MTT assay (Fig. 2a). Here, SCD is linked to melanoma.