Nevertheless, monitoring and regulating suPAR levels in patients with rFSGS or other kidney disease deserve more attention, especially because experimental evidence is emerging that suggests inhibiting uPAR pathway by cyclo-RGDfv, uPAR antibody or most recently by UPARANT, a uPAR-derived small peptide with predominant anti-inflammatory action, could render renal protection [7, 9, 22]. The gene discussed is PLAUR; the disease is kidney disorder.