KAT8 and non-small cell lung carcinoma: For example, MOF, a member of the MYST family which preferentially catalyzes acetylation of lysine 16 in H3 (H3K16), shows aberrant expression in some cancer phenotypes such as breast cancer, medulloblastoma, ovarian cancer, renal cell carcinoma, and non-small cell lung cancer (NSCLC) [20].