ESR1 and breast cancer: A case-control study examining the link between BMI and risk of breast cancer in AA and non-Hispanic EA, The Women’s Contraceptive and Reproductive Experiences (CARE), reported that premenopausal ER−/PR− breast cancer is inversely associated with the BMI of a woman at 18 years of age while the current BMI exhibits positive association with postmenopausal ER+/PR+ breast cancer [102].