APC and lung carcinoma: On the other hand, Lin et al. showed that miR-3607-5p was upregulated in lung cancer tissues and cells and that miR-3607-5p overexpression promoted lung cancer A549 cells proliferation by inhibiting adenomatous polyposis coli (APC) [18], highlighting that different miRNAs from the same precursor may have different roles in different types of cancers.