The expression of PAN correlated positively with the expression of a large number of lytic cycle genes, including K6 (vMIP-1), ORF59, K8 (bZIP), ORF25 (MCP), ORF26 (VP23), and ORF65 (SCP), which were previously detected by in situ hybridization in limited numbers of KS spindle cells. Here, ADA2 is linked to Kaposi's sarcoma.