Less common syndromes and clinically relevant findings identified include multiple endocrine neoplasia type 2, carriers for ATM PVs, Von Hippel‐Lindau syndrome, CHEK2‐associated syndrome, constitutional mismatch repair deficiency, MUTYH‐associated syndrome, PALB2‐associated syndrome, hereditary leiomyomatosis, and renal cell cancer, Cowden syndrome, BRIP1‐associated syndrome, Li‐Fraumeni syndrome, NBN‐associated syndrome, and Neurofibromatosis type 1. This evidence concerns the gene CHEK2 and renal cell adenocarcinoma.