RETREG1 and neoplasm: Overexpression of FAM134B was detected in 56/122 (45.9%) of HCC tumor tissues as compared with the adjacent non‐tumor tissues, and there were 45.1% (55/122) HCC tumor tissues showed no significant difference in the expression of FAM134B, but there were only 9% (11/122) HCC tumor tissues were low expressed FAM134B.