ESR1 and invasive ductal breast carcinoma: To further dissect this into IDC subgroups, we then analyzed our progression tissue microarrays (TMAs) including normal breast tissue, ductal carcinoma in situ (DCIS), 3 groups of invasive ductal carcinomas (ER positive; HER2 positive; or TN) as well as invasive lobular carcinoma (ILC) for this phosphorylation.