We used cBioPortal (http://www.cbioportal.org/public-portal/index.do) to analyze three different available datasets, including 2509 breast cancer (BC) samples, 1105 invasive breast carcinoma (IBC, BIC) samples, or 216 metastatic breast cancers (MBC) for gene alterations such as amplification, deletion or mutational events in PIP5K1A, PIP5K1B and PIP5K1C genes. The gene discussed is PIP5K1C; the disease is breast carcinoma.