NSCLC tumors with a high TIL infiltration score were shown to have more pronounced gene expression characteristics of TRM cells including higher transcript levels for ITGAE (CD103), CD69, ITGA1 (CD49a), CXCR6, PDCD1 (PD-1), HAVCR2 (TIM3), LAG3, and TIGIT, but lower expression of KLRG1, CCR7, SELL (CD62L), and S1PR1 (102). This evidence concerns the gene HAVCR2 and non-small cell lung carcinoma.