This is underscored by analyses of bladder (66), ovarian (83), lung (84), and pancreatic cancer (85) specimens showing either a lack of co-localization between CD103-positivie TILs and e-cadherin expressing tumor cells, or a lack of correlation between e-cadherin expression levels and CD103+ TIL infiltration. The gene discussed is CDH1; the disease is familial pancreatic carcinoma.