Additionally, in a model of oxygen-induced retinopathy, acute retinal ischemia induces TReg recruitment, although this accumulation is not enough to completely prevent vascular damage by itself; but expanding TReg population by administrating IL-2/anti-IL2 monoclonal antibody complexes to mice, TRegs are able to reduce retinopathy (92). This evidence concerns the gene IL2 and retinal ischemia.