In line with those findings, a study by Chittenden et al. (28) featuring a group of 20 ACC patients, 53 benign tumor patients, and 21 healthy individuals reported that serum chemerin levels were elevated in ACC patients as compared to those with benign adrenocortical tumors, and the difference further increased when tested against healthy controls. The gene discussed is RARRES2; the disease is adrenal cortex carcinoma.