In addition, similarities were found between CSF cytokine profiles in MOG antibody-associated disorders and AQP-4 antibody-associated NMOSD, with a predominant up-regulation of T helper 17 related cytokines in the latter, whereas in MS, T helper 1 related cytokines were found (75, 76), suggesting shared immunological pathomechanisms in the two diseases. Here, AQP4 is linked to myeloid sarcoma.