In children, MOG antibodies are predictive not only of non-MS disease with a specificity of 100% but also of a recurrent non-MS disease course with a specificity of 75% including NMOSD, recurrent ON (RON), MDEM, and ADEM followed by optic neuritis (ADEMON) (48). The gene discussed is MOG; the disease is acute disseminated encephalomyelitis.