IL10 and fungal infectious disease: This certainly is the case of IL-17 which was initially proposed to be specifically produced by autoimmune pro-inflammatory Th17 cells and later discovered to be produced at much higher level by non-Th17 cells (38–40)—to play host-protective functions against fungal infection (41)—and to be co-produced with anti-inflammatory cytokines such as IL-10 (42).