• Examined the association between serum lipids and prostate cancer risk • A cohort (n = 69,735) of all men aged 35 years or older were selected from the Apolipoprotein MOrtality RISk (AMORIS), • Levels of TG, TC, glucose, LDL-C, HDL-C, ApoB, and ApoA-I were measured at baseline, was database • 2,008 men developed prostate cancer. Here, APOB is linked to Familial prostate cancer.