ISL1 and hepatocellular carcinoma: Among them we found ERBIN, previously shown to be expressed in hepatocellular carcinoma and to promote tumorigenesis (15), and FOXA1, which significantly negatively correlated with ESR1 expression (Pearson Correlation = −0.45; p = 0.014) and is known to regulate ISL1 and PPP1R14C, two other identified estrogen-related genes.