INS and familial pancreatic carcinoma: Insulin secretion (Takahashi et al., 2012).Axonal growth; endothelial sprouting (Zhang et al., 2015a).Antithrombin binding (Mochizuki et al., 2003).Hypermethylation as marker in multiple cancers (Miyamoto et al., 2003).Zebrafish development (Cadwallander and Yost, 2006).Inflammatory stimuli in Monocytes (Sikora et al., 2016).Promotes Angiogenesis (Zhang et al., 2001).Marker for breast cancer (Mao et al., 2016).Novel inducer of Pancreatic cancer (Song et al., 2011).Cardiac Rhythm (Samson et al., 2013).