We performed some analysis to see whether IL-6 and PCR were associated with atopic or nonatopic asthma in our cohort and we found a higher OR for a mean IL-6 in the third tertile at 18 and at 22 years for the phenotype wheezing and not for atopy, although most of the results were not statically significant; the OR for IL-6 and for CRP with atopy was protective (data not shown). The gene discussed is IL6; the disease is asthma.