HMGCLL1 and chronic myelogenous leukemia, BCR-ABL1 positive: In our study, blockade of HMGCLL1 using siRNA significantly reduced the growth of BCR-ABL1+ cells, including K562, CML-T1, BaF3 wild-type, BaF3/T315Imut, and K562/T315Imut cell lines.