The level of IFNAR1 mRNA was also higher in 4/5 HNSCC cell lines than that in the control cell line (Fig. 1e), and the protein level of IFNAR1 was also increased in the tumour tissues compared with that in the adjacent normal tissues in 4/5 HNSCC patients (Fig. 1f, Supplementary Fig. S3). This evidence concerns the gene IFNAR1 and neoplasm.