In contrast, positive correlation between IFNAR1 and PDL1 expression was observed in the 108 HNSCC patients (r = 0.425, P < 0.010, Fig. 2e, f), and a frequent PDL1 gene amplification was also detected in several HNSCC subtype tumours from TCGA database (Supplementary Fig. S6). The gene discussed is CD274; the disease is head and neck squamous cell carcinoma.