Finally, it is worth noting that diverse types of cancer cells (Shu et al., 2016) are “addicted” to high BRD4 levels to maintain a pro-proliferative transcriptional program, which could negatively impact the expression levels of BRD2 and BRD3, which in the case of BRD3 could contribute to increased proliferation. This evidence concerns the gene BRD2 and cancer.