We also revealed additional genetic disorders as secondary findings in known disease genes in 10% of patients (Asthenozoospermia, late-onset mild hearing impairment, predisposition to endocrine tumors and adrenal Cushing syndrome, Noonan syndrome 5, left ventricular noncompaction 7, MPO deficiency; Supplementary Table S8). This evidence concerns the gene MPO and Reduced sperm motility.