Several transcripts encoding known inflammatory mediators are upregulated in AKI (Tnf, Ccl2 (Mcp-1), Tlr2, Trl4, IL6, IL10, IL18, Cox2, Icam1 and Vcam1) (Fig. S1), but the expression levels of some of these genes decreased in the CKD phase (Fig. 3A). This evidence concerns the gene TLR2 and acute kidney injury.