ITGAD and Glucose intolerance: In order to determine if the residual BAT in Ad-B2(−/−) female mice was offering any protection from developing glucose intolerance, we placed a separate cohort of eleven week old B2(fl/fl), Ad-B2(+/−) and Ad-B2(−/−) female mice at thermoneutral housing conditions (30 °C) for a period of nine weeks.