Our previous work consistently demonstrated electrophysiological alterations of DRD2 in the population of striatal cholinergic interneurons (ChIs) in multiple DYT1 dystonia models (Pisani et al, 2006; Sciamanna et al, 2011, 2012a; Martella et al, 2014). The gene discussed is DRD2; the disease is early-onset generalized limb-onset dystonia.