Of the 24 signals, after exclusion of FLG (table 2), three were novel for asthma (figure 3): the sentinel SNP rs10905284 in GATA3 (coded allele A, odds ratio [OR] 0·90, 95% CI 0·88–0·93; p=1·76 × 10−10) and rs11603634 in the MUC5AC region (coded allele G, OR 1·09, 1·06–1·12; p=2·32 × 10−8). Here, GATA3 is linked to asthma.