The arrays showed that STAT3, Rho, and Rac1 differed by more than two-fold in GBM-R2I2 cells compared to GBM-Par cells, and other invasive molecules such as Vimentin, N- or E-cadherin, MMP2, and MMP9 were present (Figure 1A). This evidence concerns the gene MMP2 and glioblastoma.