We further found that low tumor miR-2110 levels were correlated with high tumor TSKU mRNA levels, and that both low miR-2110 and high TSKU mRNA levels were correlated with poor neuroblastoma patient survival, suggesting that the miR-2110-mediated down-regulation of TSKU expression is an important determinant of neuroblastoma prognosis. Here, TSKU is linked to neuroblastoma.