LMNA and Hutchinson-Gilford progeria syndrome: Hutchinson‐Gilford Progeria Syndrome (HGPS) is caused by LMNA gene mutation and expression of a mutant lamin A protein called progerin, which disrupts nuclear architecture and genome stability and function, promoting cellular senescence (Collins, 2016; Gonzalo & Kreienkamp, 2015; Prokocimer, Barkan, & Gruenbaum, 2013).