While interactions with the components of B‐cell receptor signaling or TGF‐beta receptor signaling pathways were not surprising, given the prevalence of MLL1 fusions in leukemia (Buchner and Muschen, 2014; Rouce et al., 2016), the observation of extensive interactions with components of the EGFR and androgen signaling pathways was intriguing, as these pathways are primarily dysregulated in solid tumors. Here, EGFR is linked to leukemia.