Furthermore, immunohistochemistry (IHC) was used to compare the location distribution of β-catenin in cervical cancer tissues from 40 patients with mutant PIK3CA and 20 patients with wild-type PIK3CA. Representative images of β-catenin in the membrane, cytoplasm, and nucleus are presented in Fig. 3f. The gene discussed is PIK3CA; the disease is cervical cancer.