IGHE and lung disorder: By itself, the coexistence of NTM and Aspergillus in lung airway justifies the need for testing Aspergillus serology, total serum immunoglobulin (Ig)E and Aspergillus-specific IgE levels as well as mycological direct examination and culture of sputum or bronchial aspirates for presence of filamentous fungi in the diagnosis algorithm of patients with NTM lung diseases.