Molecular imaging agents have been developed for specific detection of GLP-1R in insulin-secreting pancreatic β-cells and insulinomas.14,15 Recently, positron emission tomography (PET) with 18F-FBEM-Cys40-exendin-4, revealed up-regulation of GLP-1R expression in the myocardium after acute ischemic myocardial injury in rats.16 However, the relationship between GLP-1R expression and the mechanisms involved in healing of MI and LV remodeling remains unknown. This evidence concerns the gene GLP1R and myocardial infarction.