Compared with the sham-operation, the area of α-SMA staining also increased in the remote myocardium at 1 week (1.9 ± 0.73%, P = 0.0087) and at 12 weeks (1.8 ± 0.70%, P = 0.030) after MI (Figure 1B). The gene discussed is ACTA1; the disease is myocardial infarction.