We tested the cytotoxic activities of five anticancer drugs including an Akt inhibitor (MK2206), EF24, gemcitabine (the current chemotherapeutic drug for pancreatic cancer), HSP90 inhibitor (STA9090), p38 MAPK inhibitor, and UBS109 against four different human pancreatic cancer cells MiaPaca-2 (no tissue factor (TF)-expressed), ASPC-1 (full length TF expressed), PT45P1 (full length TF expressed) and PT45P1/asTF+ (alternatively spliced TF over-expressed) in collaboration with Dr. Vladimir Y Bogdanov, University of Cincinnati. The gene discussed is AKT1; the disease is pancreatic neoplasm.