Patients with CKD exhibit a hypercoagulable state, which can be represented by elevated concentrations of hemostatic parameters like TF/VII, PAI-1, and fibrinogen (Mercier et al., 2001; Segarra et al., 2001; Gondouin et al., 2013; Shashar et al., 2015). This evidence concerns the gene SERPINE1 and thrombophilia.