The transcriptions of a set of latent genes, including EBNA1, LMP2, A73, BARF0, and RPMS1, were significantly lower in NKTCL than in NPC or GC; and the lytic genes, including BALF family and LF family are also less transcribed in NKTCL, whereas lytic genes including BBRF3, BLRF2, and BSRF1 were significantly over-expressed in NKTCL as compared to the other cancers. The gene discussed is LTF; the disease is cancer.