GLB1 and hydrops fetalis: These beta-galactosidase-positive cells were also identified in ulcer-associated dysplastic skin (Fig. 6c, d, f, h, Supplementary Figure 14b) and were observed primarily in the lower HF (Fig. 6a-III, a-IV) with the occasional entire HF in hyperplastic (Fig. 6a-I, a-II) and dysplastic epidermis being positive (Fig. 6d, h, f).