In total, 12 of the 328 genes (NALCN, CX3CR1, DSP, MGP, CELSR1, KIAA1107, EMB, GREB1L, GAD2, LGI2, SLC6A1, and TONSL) were differentially expressed in the same direction in the stem cell models and both PSP brain regions (Fig. 6c). Here, CELSR1 is linked to supranuclear palsy, progressive, 1.