Our data also show several more DMPs located within or near the TSS of tumor-related genes, including SNORD12B—previously associated with colorectal and breast cancer pathogenesis [35–37], MUC4—promising prognostic marker and therapeutic target in the case of pancreatic cancer [38–40], KIAA1614 with promoter hypermethylation observed in colon tissues from patients with ulcerative collitis as well as in colon cancer cell lines [41], and UPF1 with indisputably crucial role in the maintenance of genome stability, significantly implicated in various malignancies [42–47]. Here, MUC4 is linked to malignant colon neoplasm.