Mitulescu et al. analyzed the influence of vitamin D in patients with ankylosing spondylitis in terms of the development of acute anterior uveitis (AAU) and showed an association between low 25(OH)D and AAU accompanied by increased IL-8 and serum amyloid A as markers of the inflammatory response [22]. This evidence concerns the gene CXCL8 and ankylosing spondylitis.