Lentiviral transduction of different CaBPs was carried out in three human MM cell lines: MSTO-211H, composed of mostly epithelioid cells and some sarcomatoid (spindle-shaped) cells and with relatively high CR levels; ZL5 with epithelioid morphology and intermediate-to-low CR levels and finally SPC111, also biphasic, however, with a large proportion of spindloid cells and characterized by very low endogenous CR expression levels [20]. Here, CALB2 is linked to Miyoshi myopathy.