CCAT2 expression was higher in MDA-MB-231 and LCC9 TAM-resistant breast cancer cells derived from MCF-7 cells than in parental MCF-7 cells, and knockdown of CCAT2 inhibited the activation of TGFβ signaling in LCC9 and MCF-7 cells [312]. The gene discussed is TGFB1; the disease is breast cancer.