CD4 and neoplasm: Our findings are also supported by a study that used adoptively transferred OT-II CD4+ T cells into tumor-bearing mice that showed that lymphoma-educated C/EBPβ competent DCs reduced OT-II CD4+ T cell proliferation and that inhibition of OT-II T cell proliferation was reverted in the presence of C/EBPβ−/− DCs [50].