Second, NSCLC and MPM cell lines (H460, SKLU-1, H1299, H2052 and 211H) with increased PD-L1 protein and mRNA expression had a lower p-YAP/YAP ratio and increased GTIIC reporter activity of the Hippo pathway compared to other NSCLC and MPM cell lines with low PD-L1 protein and mRNA expression. Here, CD274 is linked to non-small cell lung carcinoma.