As shown in Figure 5, we found that the established model had the highest tdAUC (0.832) for serum biochemical markers and tumor characteristics, compared with that for previously reported indicators, including tumor number ≥3 (0.547, P = .0005), tumor diameter ≥5 cm (0.514, P < .0001), AFP ≥1000 ng/mL (0.583, P = .0020), hypersplenism (0.604, P = .0026), and ascites (0.640, P = .0031).[17–20]. This evidence concerns the gene AFP and hypersplenism.